Horst Frank

A spaceship returns to Earth after several years of space exploration and finds it desolate. Landing in what they believe is Mexico, the crew decides to travel north, and try to find out what happened to Earth during the years they were gone.

A scientist invents a serum that keeps a dog's head alive after its body dies. When the scientist dies of a heart attack, his crazed assistant cuts off his head and, using the serum, keeps the doctor's head alive and forces it to help him on an experiment to give his hunchbacked nurse assistant a new body.